Tri-State Map To help you plan your visit to À¶Ý®ÊÓƵ in Kirksville, here are some mileage estimates from cities in our tri-state area which includes Missouri, Iowa, and Illinois: Distance to Kirksville Columbia, MO: 88 miles Des Moines, IA: 150 miles Kansas City, MO:  180 miles Quad Cities, IA/IL: 186 miles St. Louis, MO: 200 miles Springfield, IL: 208 miles Springfield, MO: 260 miles Cape Girardeau: 319 miles Chicago, IL: 384 miles Why Truman Visit À¶Ý®ÊÓƵ Online Request Info